Gorgeous Upscale 8-bedroom Retreat on Thompson Lake in Otisfield, Maine | House in Otisfield

Nestled among the trees along the peaceful shores of Thompson Lake in Otisfield, Maine, 25 Panacea is an evergreen oasis where home-like comfort meets the natural beauty of water, woods, and sky. The home offers a serene, private setting ideal for large family gatherings, allowing everyone to come together while still enjoying quiet, personal space. 25 Panacea includes an expansive three-level, six-bedroom home, along with a quaint two-bedroom apartment above the detached garage. For even larger gatherings, please inquire about 35 Panacea, our neighboring property.
The main house offers six well-appointed bedrooms: four with king beds—three featuring en suite baths and twin daybeds perfect for children—one bedroom with two full beds, and one with a queen bed. Our beds feature very comfortable memory foam mattresses with premium hypoallergenic pillows. A spacious basement living area adds even more flexibility for additional guests, with two pull-out queen sofas. There are four full bathrooms, including one with an oversized soaking tub and a Kohler heated air tub. The separate two-bedroom apartment includes two king beds and one queen bed, a shower, and a kitchenette with a dining table.
Mornings on the lake begin on the wraparound porch, where rocking chairs overlook Thompson Lake and the surrounding evergreens, creating a tranquil setting for coffee and conversation. Just steps from the home, a private T-dock, floating swim-up raft, canoe, and kayaks offer endless summer fun. Thompson Lake Marina offers boat rentals for water skiing, tubing, or leisurely cruises along the shoreline. The outdoor fun goes beyond the lake—enjoy games like cornhole, ping pong, and bocce ball, perfect for friendly competition.
The fully equipped gourmet kitchen features double ovens, gas and electric stovetops, and all essential appliances, centered around a large island with seating for four. It opens seamlessly into the dining area overlooking the lake, where the dining table comfortably seats 12 and can expand to accommodate 20+ guests. There is a comfortable seating area for up to eight, ideal for reading, doing puzzles, taking an afternoon rest, or enjoying relaxed evenings together. Adjacent to this space is a cozy conversation area overlooking the lake, set in front of the wood stove. Abundant windows frame serene lake views, and the space is complemented by screened-in porches, including one off the main-floor bedroom.
Summer evenings in Maine wouldn’t be complete without a campfire. Gather around the Solo Stove to roast s’mores and take in the endless, star-filled sky. Our home is equipped with two TV rooms with Smart TVs, an exercise area including a Peloton bike, treadmill, and free weights, as well as a pool table and a large selection of card and board games.
When vacationing in Otisfield, Maine, there’s plenty to explore beyond the lake. Just a short drive brings you to Portland, with its charming streets, boutique shops, and renowned restaurants. Families and hobbyists can try nearby gemstone mining for a hands-on adventure, or spend a leisurely day antiquing through local shops and markets, uncovering unique treasures. For a true taste of Maine, pick up fresh lobsters from Smedberg’s—perfect for a lakeside feast back at the home—and savor the flavors of the coast without leaving the serene surroundings of Thompson Lake.
Amenities
Location & Outdoor Features:
Lakefront property on Thompson Lake
Private setting surrounded by trees
Private T-dock
Floating swim-up raft
Wraparound porch with rocking chairs
Screened-in porches
Outdoor seating areas
Solo Stove
Outdoor games: cornhole, bocce ball, ping pong
Water Activities
Swimming
Canoe
Kayaks
Fishing
Nearby boat rentals (Thompson Lake Marina)
Kitchen & Dining
Fully equipped gourmet kitchen
Double ovens
Gas and electric stovetops
2 refrigerators
2 beverage refrigerators
Microwave, dishwasher
Coffee maker
Large kitchen island (seats 4)
Dining table (seats 12, expands to 20+)
Living & Entertainment
Multiple living areas
Wood stove
2 TV rooms with Smart TV's
3 bedrooms with TV's
Pool table
Board games and card games
Art Supplies
High-speed Wi-Fi
Bedrooms & Bathrooms
First Floor:
Bedroom 1- King bed, ensuite bathroom (shower) shared with common areas, private screened-in porch connected to front porch.
Second Floor:
Bedroom 2- (Master) King bed, twin daybed, TV, private ensuite bathroom with duel shower heads, expansive view of the Lake
Bedroom 3- 2 double beds, Lakeside
Bedroom 4- Queen bed facing driveway.
Second Floor Bath- Oversized bathtub and single shower.
Basement:
Bedroom 5- King bed, twin daybed, Smart TV, ensuite bathroom with Kohler heated Airtub/ shower combo, bathroom shared with common area.
Bedroom 6- King bed, twin daybed, Smart TV
Additional Sleeping in Basement TV room- 2 queen pull out sofa beds.
Apartment Above Garage
Bedroom 1: King bed
Bedroom 2: Queen bed
King bed in Living Area.
Bathroom with single shower.
Fitness & Wellness
Peloton bike
Treadmill
Free weights
Essentials
Washer and dryer
Heating
Parking on site
Family-friendly

Gorgeous Upscale 8-bedroom Retreat on Thompson Lake in Otisfield, Maine is located in Oxford. Gorgeous Upscale 8-bedroom Retreat on Thompson Lake in Otisfield, Maine provides accommodation, featuring among other amenities. This House features to make your stay a comfortable one.

Gorgeous Upscale 8-bedroom Retreat on Thompson Lake in Otisfield, Maine has 9 Bedrooms , 4 Bathrooms, and max occupancy of 25 people. The minimum rental for this property is 1 nights, but this can change depending on the season you plan on staying. Previous guests have given good rated it, and VRBO labeled it a top-rated House because of the excellent services rendered by the owner or manager of this House, and has consistently provided great experiences for their guests. Most families or guests that use it recommend it to their friends and some of them are repeat guests. House has a friendly neighborhood, and the Oxford has interesting places to visit. If you want to learn more about the House in Oxford, such as places to visit and things to do nearby, you can check below to learn more.